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Identification of a consensus motif in substrates bound by a Type I Hsp40
Protein aggregation is a hallmark of a large and diverse number of conformational diseases. Molecular chaperones of the Hsp40 family (Escherichia coli DnaJ homologs) recognize misfolded disease proteins and suppress the accumulation of toxic protein species. Type I Hsp40s are very potent at suppress...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2708756/ https://ncbi.nlm.nih.gov/pubmed/19549854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900746106 |
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