Positive selection optimizes the number and function of MHCII-restricted CD4(+) T cell clones in the naive polyclonal repertoire

T cell receptors (TCRs) on T lymphocytes in an individual bind foreign peptides bound to major histocompatibility complex (MHC) molecules expressed in that individual (designated MHC(A)). Results from radiation bone marrow chimeras and TCR transgenic mice indicate that this complex form of antigen r...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Chu, H. Hamlet, Moon, James J., Takada, Kensuke, Pepper, Marion, Molitor, Jerry A., Schacker, Timothy W., Hogquist, Kristin A., Jameson, Stephen C., Jenkins, Marc K.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2009
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708705/
https://ncbi.nlm.nih.gov/pubmed/19541603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902015106
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky