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Naïve CD4+ T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude
Cell-mediated immunity stems from the proliferation of naïve T lymphocytes expressing T cell antigen receptors (TCR) specific for foreign peptides bound to host Major Histocompatibility Complex (MHC) molecules. Due to the tremendous diversity of the T cell repertoire, naïve T cells specific for any...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2200089/ https://ncbi.nlm.nih.gov/pubmed/17707129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.07.007 |
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