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The naive T-cell receptor repertoire has an extremely broad distribution of clone sizes

The clone size distribution of the human naive T-cell receptor (TCR) repertoire is an important determinant of adaptive immunity. We estimated the abundance of TCR sequences in samples of naive T cells from blood using an accurate quantitative sequencing protocol. We observe most TCR sequences only...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: de Greef, Peter C, Oakes, Theres, Gerritsen, Bram, Ismail, Mazlina, Heather, James M, Hermsen, Rutger, Chain, Benjamin, de Boer, Rob J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080410/
https://ncbi.nlm.nih.gov/pubmed/32187010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49900
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