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Coronavirus Genetically Redirected to the Epidermal Growth Factor Receptor Exhibits Effective Antitumor Activity against a Malignant Glioblastoma

Coronaviruses are positive-strand RNA viruses with features attractive for oncolytic therapy. To investigate this potential, we redirected the coronavirus murine hepatitis virus (MHV), which is normally unable to infect human cells, to human tumor cells by using a soluble receptor (soR)-based expres...

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主要な著者: Verheije, Monique H., Lamfers, Martine L. M., Würdinger, Thomas, Grinwis, Guy C. M., Gerritsen, Winald R., van Beusechem, Victor W., Rottier, Peter J. M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708613/
https://ncbi.nlm.nih.gov/pubmed/19439466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00495-09
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