Redirecting Coronavirus to a Nonnative Receptor through a Virus-Encoded Targeting Adapter

Murine hepatitis coronavirus (MHV)-A59 infection depends on the interaction of its spike (S) protein with the cellular receptor mCEACAM1a present on murine cells. Human cells lack this receptor and are therefore not susceptible to MHV. Specific alleviation of the tropism barrier by redirecting MHV t...

Full description

Saved in:
Bibliographic Details
Main Authors: Verheije, M. H., Würdinger, T., van Beusechem, V. W., de Haan, C. A. M., Gerritsen, W. R., Rottier, P. J. M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346946/
https://ncbi.nlm.nih.gov/pubmed/16415002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.3.1250-1260.2006
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items