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Redirecting Coronavirus to a Nonnative Receptor through a Virus-Encoded Targeting Adapter

Murine hepatitis coronavirus (MHV)-A59 infection depends on the interaction of its spike (S) protein with the cellular receptor mCEACAM1a present on murine cells. Human cells lack this receptor and are therefore not susceptible to MHV. Specific alleviation of the tropism barrier by redirecting MHV t...

詳細記述

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書誌詳細
主要な著者: Verheije, M. H., Würdinger, T., van Beusechem, V. W., de Haan, C. A. M., Gerritsen, W. R., Rottier, P. J. M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346946/
https://ncbi.nlm.nih.gov/pubmed/16415002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.3.1250-1260.2006
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