Upstream Regulatory Region Alterations Found in Human Papillomavirus Type 16 (HPV-16) Isolates from Cervical Carcinomas Increase Transcription, ori Function, and HPV Immortalization Capacity in Culture

Human papillomavirus (HPV) DNAs isolated from cervical and head and neck carcinomas frequently contain nucleotide sequence alterations in the viral upstream regulatory region (URR). Our study has addressed the role such sequence changes may play in the efficiency of establishing HPV persistence and...

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Detalhes bibliográficos
Main Authors: Lace, Michael J., Isacson, Christina, Anson, James R., Lörincz, Attila T., Wilczynski, Sharon P., Haugen, Thomas H., Turek, Lubomír P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Transformation and Oncogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708609/
https://ncbi.nlm.nih.gov/pubmed/19458011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00285-09
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