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Upstream Regulatory Region Alterations Found in Human Papillomavirus Type 16 (HPV-16) Isolates from Cervical Carcinomas Increase Transcription, ori Function, and HPV Immortalization Capacity in Culture

Human papillomavirus (HPV) DNAs isolated from cervical and head and neck carcinomas frequently contain nucleotide sequence alterations in the viral upstream regulatory region (URR). Our study has addressed the role such sequence changes may play in the efficiency of establishing HPV persistence and...

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Главные авторы: Lace, Michael J., Isacson, Christina, Anson, James R., Lörincz, Attila T., Wilczynski, Sharon P., Haugen, Thomas H., Turek, Lubomír P.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708609/
https://ncbi.nlm.nih.gov/pubmed/19458011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00285-09
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