Human Papillomavirus Type 16 (HPV-16) Genomes Integrated in Head and Neck Cancers and in HPV-16-Immortalized Human Keratinocyte Clones Express Chimeric Virus-Cell mRNAs Similar to Those Found in Cervical Cancers

Many human papillomavirus (HPV)-positive high-grade lesions and cancers of the uterine cervix harbor integrated HPV genomes expressing the E6 and E7 oncogenes from chimeric virus-cell mRNAs, but less is known about HPV integration in head and neck cancer (HNC). Here we compared viral DNA status and...

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Main Authors: Lace, Michael J., Anson, James R., Klussmann, Jens P., Wang, Dong Hong, Smith, Elaine M., Haugen, Thomas H., Turek, Lubomir P.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2011
Assuntos:
Transformation and Oncogenesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028875/
https://ncbi.nlm.nih.gov/pubmed/21123375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02093-10
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