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The E8(∧)E2 Gene Product of Human Papillomavirus Type 16 Represses Early Transcription and Replication but Is Dispensable for Viral Plasmid Persistence in Keratinocytes

A conserved E8(∧)E2 spliced mRNA is detected in keratinocytes transfected with human papillomavirus type 16 (HPV-16) plasmid DNA. Expression of HPV-16 E8(∧)E2 (16-E8(∧)E2) is independent of the major early promoter, P97, and is modulated by both specific splicing events and conserved cis elements in...

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Autors principals: Lace, Michael J., Anson, James R., Thomas, Gregory S., Turek, Lubomir P., Haugen, Thomas H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573160/
https://ncbi.nlm.nih.gov/pubmed/18753207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01481-08
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