Interaction of the Papillomavirus E8∧E2C Protein with the Cellular CHD6 Protein Contributes to Transcriptional Repression

Expression of the E6 and E7 oncogenes of high-risk human papillomaviruses (HPV) is controlled by cellular transcription factors and by viral E2 and E8∧E2C proteins, which are both derived from the HPV E2 gene. Both proteins bind to and repress the HPV E6/E7 promoter. Promoter inhibition has been sug...

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Bibliografiske detaljer
Main Authors: Fertey, Jasmin, Ammermann, Ingo, Winkler, Michael, Stöger, Reinhard, Iftner, Thomas, Stubenrauch, Frank
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Genome Replication and Regulation of Viral Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937640/
https://ncbi.nlm.nih.gov/pubmed/20631145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00678-10
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