Chlamydial Heat Shock Protein 60 Induces Acute Pulmonary Inflammation in Mice via the Toll-Like Receptor 4- and MyD88-Dependent Pathway

Heat shock protein 60 derived from Chlamydia pneumoniae (cHSP60) activates Toll-like receptor 4 (TLR4) signaling through the MyD88 pathway in vitro, but it is not known how cHSP60 contributes to C. pneumoniae-induced lung inflammation. We treated wild-type (WT), TLR2(−/−), TLR4(−/−), or MyD88(−/−) m...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Bulut, Yonca, Shimada, Kenichi, Wong, Michelle H., Chen, Shuang, Gray, Pearl, Alsabeh, Randa, Doherty, Terence M., Crother, Timothy R., Arditi, Moshe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708574/
https://ncbi.nlm.nih.gov/pubmed/19398543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00248-09
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados