Inhibition of Rho Family Functions by Lovastatin Promotes Myelin Repair in Ameliorating Experimental Autoimmune Encephalomyelitis

Impaired remyelination is critical to neuroinflammation in multiple sclerosis (MS), which causes chronic and relapsing neurological impairments. Recent studies revealed that immunomodulatory activity of statins in an experimental autoimmune encephalomyelitis (EAE) model of MS are via depletion of is...

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Main Authors: Paintlia, Ajaib Singh, Paintlia, Manjeet Kaur, Singh, Avtar Kaur, Singh, Inderjit
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706586/
https://ncbi.nlm.nih.gov/pubmed/18239032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.107.044230
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