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Developmental expression of PrP in the post-implantation embryo

Since prion protein (PrP) mRNA and PrP(C) expression levels in transgenic (Tg) mice using the CosSHa.tet vector correlate well with the PrP transgene copy, we constructed Prnp-LacZ Tg animals expressing β-galactosidase that was inserted into the CosSHa.tet vector. The CosSHa.tet vector was created f...

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Autores principales: Tremblay, Patrick, Bouzamondo-Bernstein, Essia, Heinrich, Cornelia, Prusiner, Stanley B., DeArmond, Stephen J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706582/
https://ncbi.nlm.nih.gov/pubmed/17292334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2006.12.055
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