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Functional implications of T cell receptor diversity

Naive T cells are recruited into any given host response by recognizing a spectrum of possible antigens with “sufficient” avidity. Does selecting a more functionally diverse array give better immune control? Perhaps low avidity “killers” that “kiss and run” operate optimally to eliminate virus-infec...

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Detalhes bibliográficos
Main Authors: Turner, Stephen J, La Gruta, Nicole L, Kedzierska, Katherine, Thomas, Paul G, Doherty, Peter C
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706259/
https://ncbi.nlm.nih.gov/pubmed/19524428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2009.05.004
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