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A series of cationic sterol lipids with gene transfer and bactericidal activity
A family of cationic lipids was synthesized via direct amide coupling of spermine to the C-24 position of cholic acid analogs. Four monosubstituted spermines and a bis-substituted spermine were evaluated as plasmid transfection reagents, as bacteriostatic agents, and as bactericidal agents. The inco...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2706119/ https://ncbi.nlm.nih.gov/pubmed/19364656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.03.049 |
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