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In-vitro Investigation of Oxazol and Urea Analogues of Morphinan at Opioid Receptors
A series of 2-amino-oxazole (7 & 8) analogs and 2-one-oxazole analogs (9 &10) were synthesized from cyclorphan (1) or butorphan (2) and evaluated in-vitro by their binding affinity at μ, δ and κ opioid receptors and compared with their 2-aminothiozole analogs 5 & 6. Ligands 7–10 showed d...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2706089/ https://ncbi.nlm.nih.gov/pubmed/17433695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.03.076 |
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