Enhanced skin carcinogenesis and lack of thymus hyperplasia in transgenic mice expressing human cyclin D1b (CCND1b)

Cyclin D1b is an alternative transcript of the cyclin D1 gene (CCND1) expressed in human tumors. Its abundance is regulated by a single base pair polymorphism at the exon 4/intron 4 boundary (nucleotide 870). Epidemiological studies have shown a correlation between the presence of the G870A allele (...

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Bibliografiske detaljer
Main Authors:	Rojas, Paola, Benavides, Fernando, Blando, Jorge, Perez, Carlos, Cardenas, Kim, Richie, Ellen, Knudsen, Erik S., Johnson, David G., Senderowicz, Adrian M., Rodriguez-Puebla, Marcelo L., Conti, Claudio J.
Format:	Artigo
Sprog:	Inglês
Udgivet:	2009
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2705965/ https://ncbi.nlm.nih.gov/pubmed/18942117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20489
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Enhanced skin carcinogenesis and lack of thymus hyperplasia in transgenic mice expressing human cyclin D1b (CCND1b)

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