Enhanced skin carcinogenesis and lack of thymus hyperplasia in transgenic mice expressing human cyclin D1b (CCND1b)

Cyclin D1b is an alternative transcript of the cyclin D1 gene (CCND1) expressed in human tumors. Its abundance is regulated by a single base pair polymorphism at the exon 4/intron 4 boundary (nucleotide 870). Epidemiological studies have shown a correlation between the presence of the G870A allele (...

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Detalhes bibliográficos
Main Authors: Rojas, Paola, Benavides, Fernando, Blando, Jorge, Perez, Carlos, Cardenas, Kim, Richie, Ellen, Knudsen, Erik S., Johnson, David G., Senderowicz, Adrian M., Rodriguez-Puebla, Marcelo L., Conti, Claudio J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705965/
https://ncbi.nlm.nih.gov/pubmed/18942117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20489
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