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Measurement of Serum 7α-hydroxy-4-cholesten-3-one (or 7αC4), a Surrogate Test for Bile Acid Malabsorption in Health, Ileal Disease and Irritable Bowel Syndrome using Liquid Chromatography-Tandem Mass Spectrometry
BACKGROUND: Bile acid malabsorption (BAM) is reported in up to 50% of patients with functional diarrhea and irritable bowel syndrome with diarrhea (IBS-D). Serum 7α-hydroxy-4-cholesten-3-one (7αHCO, or 7αC4), an indirect measurement of hepatic bile acid synthesis, has been validated as a measurement...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2705747/ https://ncbi.nlm.nih.gov/pubmed/19368662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2982.2009.01288.x |
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