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Mre11-Rad50-Nbs complex is required to cap telomeres during Drosophila embryogenesis
Using Drosophila as a model system, we identified here a stringent requirement for Mre11-Rad50-Nbs (MRN) function in telomere protection during early embryonic development. Animals homozygous for hypomorphic mutations in either mre11 or nbs develop normally with minimal telomere dysfunction. However...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2705596/ https://ncbi.nlm.nih.gov/pubmed/19520832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902707106 |
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