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Substrate shuttling between active sites of uroporphyrinogen decarboxylase is not required to generate coproporphyrinogen
Uroporphyrinogen Decarboxylase (URO-D; EC 4.1.1.37), the fifth enzyme of the heme biosynthetic pathway, is required for the production of heme, vitamin B12, siroheme, and chlorophyll precursors. URO-D catalyzes the sequential decarboxylation of the four acetate side chains on the pyrrole groups of u...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2705282/ https://ncbi.nlm.nih.gov/pubmed/19362562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.04.013 |
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