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Cellular Contractility Requires Ubiquitin Mediated Proteolysis
BACKGROUND: Cellular contractility, essential for cell movement and proliferation, is regulated by microtubules, RhoA and actomyosin. The RhoA dependent kinase ROCK ensures the phosphorylation of the regulatory Myosin II Light Chain (MLC) Ser19, thereby activating actomyosin contractions. Microtubul...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2705188/ https://ncbi.nlm.nih.gov/pubmed/19597551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006155 |
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