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STRAP Regulates c-Jun Ubiquitin-mediated Proteolysis and Cellular Proliferation

STRAP is a ubiquitious WD40 protein that has been implicated in tumorigenesis. Previous studies suggest that STRAP imparts oncogenic characteristics to cells by promoting ERK and pRb phosphorylation. While these findings suggest that STRAP can activate mitogenic signaling pathways, the effects of ST...

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Main Authors: Reiner, Jennifer, Ye, Fei, Datta, Pran K.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899788/
https://ncbi.nlm.nih.gov/pubmed/21397588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.03.028
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