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Role of ubiquitin-proteasome-mediated proteolysis in nervous system disease

Proteolysis by the ubiquitin-proteasome pathway (UPP) is now widely recognized as a molecular mechanism controlling myriad normal functions in the nervous system. Also, this pathway is intimately linked to many diseases and disorders of the brain. Among the diseases connected to the UPP are neurodeg...

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Main Authors: Hegde, Ashok N., Upadhya, Sudarshan C.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995838/
https://ncbi.nlm.nih.gov/pubmed/20674814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2010.07.006
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