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Role of the ubiquitin proteasome system in Alzheimer's disease

Though Alzheimer's disease (AD) is a syndrome with well-defined clinical and neuropathological manifestations, an array of molecular defects underlies its pathology. A role for the ubiquitin proteasome system (UPS) was suspected in the pathogenesis of AD since the presence of ubiquitin immunore...

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Detalhes bibliográficos
Main Authors: Upadhya, Sudarshan C, Hegde, Ashok N
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2106363/
https://ncbi.nlm.nih.gov/pubmed/18047736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-8-S1-S12
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