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Modification at HuR(S242) Alters HuR Localization and Proliferative Influence

HuR is predominantly nuclear but following exposure to stress and mitogens, it can translocate to the cytoplasm where it stabilizes target mRNAs and/or modulates their translation. Several phosphorylation sites in a central ‘hinge’ region of HuR have been reported to affect its nucleocytoplasmic shu...

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Bibliografiska uppgifter
Huvudupphovsmän: Kim, Hyeon Ho, Yang, Xiaoling, Kuwano, Yuki, Gorospe, Myriam
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704553/
https://ncbi.nlm.nih.gov/pubmed/18948743
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