A carregar...
HuR recruits let-7/RISC to repress c-Myc expression
RNA-binding proteins (RBPs) and microRNAs (miRNAs) are potent post-transcriptional regulators of gene expression. Here, we show that the RBP HuR reduced c-Myc expression by associating with the c-Myc 3′ untranslated region (UTR) next to a miRNA let-7-binding site. Lowering HuR or let-7 levels reliev...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2009
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2720259/ https://ncbi.nlm.nih.gov/pubmed/19574298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1812509 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|