Issues in applying multi-arm multi-stage methodology to a clinical trial in prostate cancer: the MRC STAMPEDE trial

BACKGROUND: The multi-arm multi-stage (MAMS) trial is a new paradigm for conducting randomised controlled trials that allows the simultaneous assessment of a number of research treatments against a single control arm. MAMS trials provide earlier answers and are potentially more cost-effective than a...

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Hlavní autoři: Sydes, Matthew R, Parmar, Mahesh KB, James, Nicholas D, Clarke, Noel W, Dearnaley, David P, Mason, Malcolm D, Morgan, Rachel C, Sanders, Karen, Royston, Patrick
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
Methodology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704188/
https://ncbi.nlm.nih.gov/pubmed/19519885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6215-10-39
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