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Dicer independent small RNAs associate with telomeric heterochromatin

Small RNAs play important roles in the establishment and maintenance of heterochromatin structures. We show the presence of telomere specific small RNAs (tel-sRNAs) in mouse embryonic stem cells that are ∼24 nucleotides in length, Dicer-independent, and 2′-O-methylated at the 3′ terminus. The tel-sR...

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Autores principales: Cao, Fang, Li, Xiangzhi, Hiew, Samantha, Brady, Hugh, Liu, Yifan, Dou, Yali
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704082/
https://ncbi.nlm.nih.gov/pubmed/19460867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1423309
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