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Dicer independent small RNAs associate with telomeric heterochromatin

Small RNAs play important roles in the establishment and maintenance of heterochromatin structures. We show the presence of telomere specific small RNAs (tel-sRNAs) in mouse embryonic stem cells that are ∼24 nucleotides in length, Dicer-independent, and 2′-O-methylated at the 3′ terminus. The tel-sR...

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Detalhes bibliográficos
Main Authors: Cao, Fang, Li, Xiangzhi, Hiew, Samantha, Brady, Hugh, Liu, Yifan, Dou, Yali
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704082/
https://ncbi.nlm.nih.gov/pubmed/19460867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1423309
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