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Production of small RNAs by mammalian Dicer

MicroRNA (miRNA) and RNA interference (RNAi) pathways employ RNase III Dicer for the biogenesis of small RNAs guiding post-transcriptional repression. Requirements for Dicer activity differ in the two pathways. The biogenesis of miRNAs requires a single Dicer cleavage of a short hairpin precursor to...

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Bibliografski detalji
Izdano u:Pflugers Arch
Glavni autori: Svobodova, Eliska, Kubikova, Jana, Svoboda, Petr
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893058/
https://ncbi.nlm.nih.gov/pubmed/27048428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-016-1817-6
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