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Processing bodies are not required for mammalian nonsense-mediated mRNA decay
Nonsense-mediated mRNA decay (NMD) is a eukaryotic quality-control mechanism that recognizes and degrades mRNAs with premature termination codons (PTCs). In yeast, PTC-containing mRNAs are targeted to processing bodies (P-bodies), and yeast strains expressing an ATPase defective Upf1p mutant accumul...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2009
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2704072/ https://ncbi.nlm.nih.gov/pubmed/19474145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1672509 |
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