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Promoter Methylation in the Genesis of Gastrointestinal Cancer

Colorectal cancers (CRC)-and probably all cancers-are caused by alterations in genes. This includes activation of oncogenes and inactivation of tumor suppressor genes (TSGs). There are many ways to achieve these alterations. Oncogenes are frequently activated by point mutation, gene amplification, o...

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Detalhes bibliográficos
Main Authors: Boland, Clement Richard, Shin, Sung Kwan, Goel, Ajay
Formato: Artigo
Idioma:Inglês
Publicado em: Yonsei University College of Medicine 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703751/
https://ncbi.nlm.nih.gov/pubmed/19568590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2009.50.3.309
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