Promoter Methylation in the Genesis of Gastrointestinal Cancer

Colorectal cancers (CRC)-and probably all cancers-are caused by alterations in genes. This includes activation of oncogenes and inactivation of tumor suppressor genes (TSGs). There are many ways to achieve these alterations. Oncogenes are frequently activated by point mutation, gene amplification, o...

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Bibliografiske detaljer
Main Authors: Boland, Clement Richard, Shin, Sung Kwan, Goel, Ajay
Format: Artigo
Sprog:Inglês
Udgivet: Yonsei University College of Medicine 2009
Fag:
Review Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703751/
https://ncbi.nlm.nih.gov/pubmed/19568590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2009.50.3.309
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