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APC Promoter Methylation in Gastrointestinal Cancer

The adenomatous polyposis coli (APC) gene, known as tumor suppressor gene, has the two promoters 1A and 1B. Researches on APC have usually focused on its loss-of-function variants causing familial adenomatous polyposis. Hypermethylation, however, which is one of the key epigenetic alterations of the...

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Foilsithe in:Front Oncol
Main Authors: Zhu, Lila, Li, Xinyu, Yuan, Ying, Dong, Caixia, Yang, Mengyuan
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103321/
https://ncbi.nlm.nih.gov/pubmed/33968756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.653222
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