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APC Promoter Methylation in Gastrointestinal Cancer

The adenomatous polyposis coli (APC) gene, known as tumor suppressor gene, has the two promoters 1A and 1B. Researches on APC have usually focused on its loss-of-function variants causing familial adenomatous polyposis. Hypermethylation, however, which is one of the key epigenetic alterations of the...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Zhu, Lila, Li, Xinyu, Yuan, Ying, Dong, Caixia, Yang, Mengyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103321/
https://ncbi.nlm.nih.gov/pubmed/33968756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.653222
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