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Shh and Gli3 activities are required for timely generation of motor neuron progenitors

Generation of distinct ventral neuronal subtypes in the developing spinal cord requires Shh signaling mediated by the Gli family of transcription factors. Genetic studies of Shh(−/−);Gli3(−/−) double mutants indicated that the inhibition of Gli3 repressor activity by Shh is sufficient for the genera...

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Bibliografische gegevens
Hoofdauteurs: Oh, SaeOck, Huang, Xi, Liu, Jiang, Litingtung, Ying, Chiang, Chin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703695/
https://ncbi.nlm.nih.gov/pubmed/19433083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.05.539
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