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Shh and Gli3 activities are required for timely generation of motor neuron progenitors
Generation of distinct ventral neuronal subtypes in the developing spinal cord requires Shh signaling mediated by the Gli family of transcription factors. Genetic studies of Shh(−/−);Gli3(−/−) double mutants indicated that the inhibition of Gli3 repressor activity by Shh is sufficient for the genera...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2703695/ https://ncbi.nlm.nih.gov/pubmed/19433083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.05.539 |
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