Tcf/Lef repressors differentially regulate Shh-Gli target gene activation thresholds to generate progenitor patterning in the developing CNS

During neural tube development, Shh signaling through Gli transcription factors is necessary to establish five distinct ventral progenitor domains that give rise to unique classes of neurons and glia that arise in specific positions along the dorsoventral axis. These cells are generated from progeni...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, Hui, Lei, Qiubo, Oosterveen, Tony, Ericson, Johan, Matise, Michael P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Company of Biologists 2011
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152926/
https://ncbi.nlm.nih.gov/pubmed/21775418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.068270
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