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An EM view of the FokI synaptic complex by single particle analysis

FokI is a Type IIS restriction endonuclease that recognizes the 5′-GGATG-3′ sequence and cleaves non-specifically at 9 and 13 base pairs away on the top and bottom strands respectively to produce a 5′ overhang. FokI is a bipartite endonuclease with separate recognition and cleavage domains. Because...

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Autori principali: Vanamee, Éva Scheuring, Berriman, John, Aggarwal, Aneel K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703192/
https://ncbi.nlm.nih.gov/pubmed/17524420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.04.066
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