Effects of 4-Vinylcyclohexene Diepoxide on Peripubertal and Adult Sprague–Dawley Rats: Ovarian, Clinical, and Pathologic Outcomes

Young rats treated daily with intraperitoneal 4-vinylcyclohexene diepoxide (VCD) undergo selective destruction of primordial follicles, resulting in gradual ovarian failure resembling the menopausal transition in women. To determine whether VCD has similar effects on ovaries of older rats, adult and...

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Main Authors: Muhammad, F Salih, Goode, Amanda K, Kock, Nancy D, Arifin, Esther A, Cline, J Mark, Adams, Michael R, Hoyer, Patricia B, Christian, Patricia J, Isom, Scott, Kaplan, Jay R, Appt, Susan E
Format: Artigo
Sprog:Inglês
Udgivet: American Association for Laboratory Animal Science 2009
Fag:
Rat Models
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703138/
https://ncbi.nlm.nih.gov/pubmed/19295054
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