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Targeting the PIAS1 SUMO ligase pathway to control inflammation

Protein sumoylation is a post-translational-modification event, in which small ubiquitin-like modifier (SUMO) is covalently attached to protein substrates by a three-step process. Sumoylation has been suggested to regulate multiple cellular processes, including inflammation. Inflammation is initiate...

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Bibliografiske detaljer
Main Authors: Liu, Bin, Shuai, Ke
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701905/
https://ncbi.nlm.nih.gov/pubmed/18755518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2008.07.008
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