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Reciprocal Regulation of Abl and Receptor Tyrosine Kinases
Previously, we showed that Abl kinases (c-Abl, Arg) are activated downstream of PDGF in a manner dependent on Src kinases and PLC-γ1, and promote PDGF-mediated proliferation and migration of fibroblasts. We additionally demonstrated that Abl kinases bind directly to PDGFR-β via their SH2 domains. In...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2701649/ https://ncbi.nlm.nih.gov/pubmed/19275932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2009.03.003 |
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