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Reciprocal Regulation of Abl and Receptor Tyrosine Kinases

Previously, we showed that Abl kinases (c-Abl, Arg) are activated downstream of PDGF in a manner dependent on Src kinases and PLC-γ1, and promote PDGF-mediated proliferation and migration of fibroblasts. We additionally demonstrated that Abl kinases bind directly to PDGFR-β via their SH2 domains. In...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Srinivasan, Divyamani, Kaetzel, David M., Plattner, Rina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701649/
https://ncbi.nlm.nih.gov/pubmed/19275932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2009.03.003
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