The Ron receptor tyrosine kinase activates c-Abl to promote cell proliferation through tyrosine phosphorylation of PCNA in breast cancer

Multiple growth pathways lead to enhanced proliferation in malignant cells. However, how the core machinery of DNA replication is regulated by growth signaling remains largely unclear. The sliding clamp PCNA (Proliferating Cell Nuclear Antigen) is an indispensable component of the DNA machinery resp...

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Hlavní autoři: Zhao, Huajun, Chen, Min-Shan, Lo, Yuan-Hung, Waltz, Susan E., Wang, Jiang, Ho, Po-Chun, Vasiliauskas, Juozas, Plattner, Rina, Wang, Yuan-Liang, Wang, Shao-Chun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064789/
https://ncbi.nlm.nih.gov/pubmed/23542172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.84
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