The Ron receptor tyrosine kinase activates c-Abl to promote cell proliferation through tyrosine phosphorylation of PCNA in breast cancer

Multiple growth pathways lead to enhanced proliferation in malignant cells. However, how the core machinery of DNA replication is regulated by growth signaling remains largely unclear. The sliding clamp PCNA (Proliferating Cell Nuclear Antigen) is an indispensable component of the DNA machinery resp...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhao, Huajun, Chen, Min-Shan, Lo, Yuan-Hung, Waltz, Susan E., Wang, Jiang, Ho, Po-Chun, Vasiliauskas, Juozas, Plattner, Rina, Wang, Yuan-Liang, Wang, Shao-Chun
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064789/
https://ncbi.nlm.nih.gov/pubmed/23542172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.84
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