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Structural Analogs of Tylophora Alkaloids may not be Functional Analogs

Phenanthroindolizidine-based tylophora alkaloids have been reported to have potential antitumor, anti-immuno and anti-inflammatory activity. The structure-activity relationships of a series of tylophora alkaloids were studied to guide future drug design. Our results indicate that although these comp...

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Bibliografiske detaljer
Main Authors: Gao, Wenli, Chen, Annie Pei-Chun, Leung, Chung-Hang, Gullen, Elizabeth A., Fürstner, Alois, Shi, Qian, Wei, Linyi, Lee, Kuo-Hsiung, Cheng, Yung-Chi
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701548/
https://ncbi.nlm.nih.gov/pubmed/18077159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.11.054
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