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A Double S Shape Provides the Structural Basis for the Extraordinary Binding Specificity of Dscam Isoforms
Drosophila Dscam encodes a vast family of immunoglobulin (Ig)-containing proteins that exhibit isoformspecific homophilic binding. This diversity is essential for cell recognition events required for wiring the brain. Each isoform binds to itself but rarely to other isoforms. Specificity is determin...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2701508/ https://ncbi.nlm.nih.gov/pubmed/18805093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.07.042 |
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