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A Double S Shape Provides the Structural Basis for the Extraordinary Binding Specificity of Dscam Isoforms

Drosophila Dscam encodes a vast family of immunoglobulin (Ig)-containing proteins that exhibit isoformspecific homophilic binding. This diversity is essential for cell recognition events required for wiring the brain. Each isoform binds to itself but rarely to other isoforms. Specificity is determin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sawaya, Michael R., Wojtowicz, Woj M., Andre, Ingemar, Qian, Bin, Wu, Wei, Baker, David, Eisenberg, David, Zipursky, S. Lawrence
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701508/
https://ncbi.nlm.nih.gov/pubmed/18805093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.07.042
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