Llwytho...

The Role of Cholesterol and Structurally Related Molecules in Enhancing Transfection by Cationic Liposome–DNA Complexes

Motivated by its important role in gene delivery, we have studied the effect of cholesterol and analogs on the transfection efficiency (TE) of lamellar cationic liposome–DNA (CL–DNA) complexes in vitro. Addition of cholesterol to low-transfecting DOTAP/DOPC–DNA complexes increases TE, with 15 mol% c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zidovska, Alexandra, Evans, Heather M., Ahmad, Ayesha, Ewert, Kai K., Safinya, Cyrus R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701310/
https://ncbi.nlm.nih.gov/pubmed/19354307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp809000e
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